Fig. 11 | Scientific Reports

Fig. 11

From: Development of novel canine phage display-derived neutralizing monoclonal antibody fragments against rabies virus from immunized dogs

Fig. 11

Three-dimensional (3D) tertiary structure prediction of the K9RABVscFv1 and K9RABVscFv16 antibodies and the rabies virus glycoprotein (RABV-G). PDBID no. 1 × 9q, 8dy2.1. A and the monomer form of PDBID no. 7u9g were used as templates for K9RABVscFv1, K9RABVscFv16, and RABV-G protein structure simulations. The light purple and pink clusters represent the VL and VH chains, respectively. The orange fragment was a glycine/serine linker (G/S linker). CDR1–3 on the VH and VL chains are shown in several colors. Surface display and line-ribbon style of (a) K9RABVscFv1, (b) K9RABVscFv16, and (c) RABV-G (SQ382). The SWISS model online server (https://swissmodel.expasy.org/) was used to construct protein structure homology models, which were decorated with BIOVIA Discovery Studio Visualizer 2021.

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