Table 19 The \({R}^{2}\) values between computed topological indices and ADMET properties of the tuberculosis treatment drugs.
Indices | Properties | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
\(\text{WS}\) | IA | FU | BBB | \(\text{CNS}\) | \(\text{TC}\) | \(\text{AT}\) | MTD | CT | TPY | |
\(DW\) | 0.789 | 0.837 | 0.606 | 0.932 | 0.618 | 0.511 | 0.658 | 0.486 | 0.178 | 0.680 |
\(DHW\) | 0.744 | 0.549 | 0.845 | 0.905 | 0.471 | 0.538 | 0.763 | 0.651 | 0.303 | 0.767 |
\(DTW\) | 0.813 | 0.934 | 0.461 | 0.775 | 0.595 | 0.692 | 0.679 | 0.132 | 0.406 | 0.592 |
\(DH\) | 0.739 | 0.535 | 0.376 | 0.910 | 0.375 | 0.166 | 0.404 | 0.635 | 0.075 | 0.585 |
\(DSC\) | 0.796 | 0.814 | 0.552 | 0.935 | 0.607 | 0.442 | 0.609 | 0.528 | 0.136 | 0.672 |
\(DS{C}^{*}\) | 0.858 | 0.179 | 0.711 | 0.925 | 0.173 | 0.165 | 0.674 | 0.880 | 0.407 | 0.851 |
\(DA\) | 0.990 | 0.879 | 0.761 | 0.927 | 0.579 | 0.799 | 0.931 | 0.435 | 0.619 | 0.899 |
\(DSM\) | 0.911 | 0.675 | 0.930 | 0.862 | 0.460 | 0.771 | 0.980 | 0.763 | 0.805 | 0.996 |
