Table 2 The results of the four MR menthods.

From: The relationship between diverticular disease of intestine and cirrhosis: a two-sample mendelian randomization study

Exposure

Outcome

Method

Nsnp

OR(95%CI)

P

Diverticular disease of intestine

Cirrhosis

IVW

56

0.849(0.743–0.971)

0.016462419

Diverticular disease of intestine

Cirrhosis

MR Egger

56

0.678(0.466–0.988)

0.047792323

Diverticular disease of intestine

Cirrhosis

WM

56

0.791(0.650–0.962)

0.019127643

Diverticular disease of intestine

Cirrhosis

Weighted mode

56

0.766(0.603–0.973)

0.033131418

Diverticular disease of intestine

Cirrhosis

ConMix

56

0.856(0.740–0.990)

0.036557168

Diverticular disease of intestine

Cirrhosis

RAPS

56

0.851(0.742–0.976)

0.020941844

Diverticular disease of intestine

Cirrhosis

DIVW

56

0.846(0.739–0.969)

0.015925034

Diverticular disease of intestine

Cirrhosis

cML-MA

56

0.852(0.736–0.987)

0.032819224

  1. IVW: inverse variance weighted; WM: weighted median; ConMix: contamination mixture; RAPS: robust adjusted profile score; DIVW: debiased inverse-variance weighted method; cML-MA: constrained maximum likelihood; OR: odds ratio; CI: confidence interval.
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