Fig. 6 | Scientific Reports

Fig. 6

From: Pharmacokinetic and pharmacodynamic evaluation of various vasopressin doses and routes of administration in a neonatal piglet model

Fig. 6

(I) Maximum vasopressin plasma concentration, (II) AUC (area under the curve) from baseline to 10 min, (III) time to maximum plasma concentration, (IV) clearance, and (V) half-life. Data are presented as mean (SD). IV, intravenous (red); IO, intraosseous (blue); ET, endotracheal (green); and IN, intranasal (grey). a, significantly different from the IV vasopressin group; b, significantly different from the 0.2IU/kg IO group; c, significantly different from the 0.8IU/kg IO group; d, significantly different from the 8IU/kg IN group; e, significantly different from the 16IU/kg IN group; f, significantly different from the 32IU/kg IN group (p < 0.05).

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