Fig. 3
Mice that underwent ovariectomy + LIM showed more myopic refraction status and deeper anterior chamber than LIM without ovariectomy. (a) Both sham control and ovariectomized mice indicated myopia in -30D lens eyes, and ovariectomized mice showed more myopic shift than the sham control mice. (b,c,e,f,g) No significant difference was found in the AL, corneal thickness, lens thickness, vitreous body thickness, and choroidal thickness of frame-treated eyes or the − 30 D lens-treated eyes, and no difference was found in the sham control and ovariectomy groups. (d) ACD was deeper in ovariectomized mice than that in the sham control mice and deeper in -30 D lens-treated eyes than the frame-treated eyes of ovariectomized mice. n = 6 in control group, n = 5 in OVX group. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, two-way ANOVA tests.
