Table 5 Positive changes reported and psychedelics used on a regular basis.

Increased capacity of self-observation

Psilocybin mushrooms (66.4%, χ² = 70.79, p < 0.01)

LSD (36.1%, χ² = 39.11, p < 0.01)

MDMA (30%, χ² = 35.97, p < 0.01)

San Pedro cactus (14.1%, χ² = 42.44, p < 0.01)

Synthetic DMT (12.4%, χ² = 45.35, p < 0.01)

Ayahuasca (10.5%, χ² = 39.62, p < 0.01)

Floripondium (3%, χ² = 34.19, p < 0.01)

Improved mood

Psilocybin mushrooms (57.4%, χ² = 43.26, p < 0.01)

San Pedro cactus (19.8%, χ² = 35.70, p < 0.01)

Personal growth

Psilocybin mushrooms (54.1%, χ² = 67.12, p < 0.01)

LSD (53.8%, χ² = 36.60, p < 0.01)

San Pedro cactus (12.4%, χ² = 43.54, p < 0.01)

Ayahuasca (10.1%, χ² = 47.43, p < 0.01)

Synthetic DMT (9.6%, χ² = 35.24, p < 0.01)

Floripondium (2.9%, χ² = 35.27, p < 0.01)

Heightened sensitivity

Psilocybin mushrooms (52.9%, χ² = 61.75, p < 0.01)

Ayahuasca (18.3%, χ² = 36.39, p < 0.01)

DMT-Tepezcohuite (13.2%, χ² = 35.01, p < 0.01)

San Pedro cactus (12.9%, χ² = 42.83, p < 0.01)

Synthetic DMT (9.2%, χ² = 37.42, p < 0.01)

Spiritual growth

Psilocybin mushrooms (51.1%, χ² = 55.71, p < 0.01)

Ayahuasca (19.4%, χ² = 53.52, p < 0.01)

San Pedro cactus (13.1%, χ² = 54.22, p < 0.01)

Synthetic DMT (10.1%, χ² = 40.69, p < 0.01)

DMT-Tepezcohuite (9.3%, χ² = 35.36, p < 0.01)

Peyote (8.7%, χ² = 39.63, p < 0.01)

Floripondium (2.8%, χ² = 36.16, p < 0.01)

Decrease in anxiety and/or distress

Psilocybin mushrooms (49.9%, χ² = 40.65, p < 0.01)

DMT-Tepezcohuite (6.2%, χ² = 35.31, p < 0.01)

Positive changes in my eating, hygiene and/or self-care habits

Psilocybin mushrooms (47.5%, χ² = 43.66, p < 0.01)

Increased questioning of my work, relationships and/or habits, without discomfort

Psilocybin mushrooms (43%, χ² = 40.41, p < 0.01)

LSD (19.9%, χ² = 35.57, p < 0.01)

MDMA (17.3%, χ² = 36.92, p < 0.01)

Synthetic DMT (8.4%, χ² = 44.49, p < 0.01)

San Pedro cactus (7.7%, χ² = 34.86, p < 0.01)

Decreased fear of dying and/or of losing something/someone

Ayahuasca (44%, χ² = 42.43, p < 0.01)

Psilocybin mushrooms (22%, χ² = 39.66, p < 0.01)

Synthetic DMT (15.2%, χ² = 42.31, p < 0.01)

LSD (12.8%, χ² = 35.13, p < 0.01)

DMT-Tepezcohuite (5.4%, χ² = 43.74, p < 0.01)

San Pedro cactus (5.2%, χ² = 34.83, p < 0.01)

Peyote (3.3%, χ² = 42.85, p < 0.01)

Increased problem-solving skills

Psilocybin mushrooms (39.1%, χ² = 52.65, p < 0.01)

San Pedro cactus (22.8%, χ² = 38.56, p < 0.01)

DMT-Tepezcohuite (12%, χ² = 39.11, p < 0.01)

Ayahuasca (7.4%, χ² = 36.09, p < 0.01)

Synthetic DMT (8%, χ² = 38.81, p < 0.01)

Changes in my recreational interests

Psilocybin mushrooms (38.6%, χ² = 41.65, p < 0.01)

Ayahuasca (29%, χ² = 37.88, p < 0.01)

San Pedro cactus (18.8%, χ² = 35.71, p < 0.01)

LSD (16.6%, χ² = 34.70, p < 0.01)

MDMA (15.5%, χ² = 40.87, p < 0.01)

Synthetic DMT (12.6%, χ² = 34.10, p < 0.01)

DMT-Tepezcohuite (12%, χ² = 38.47, p < 0.01)

Peyote (3%, χ² = 46.48, p < 0.01)

General reduction of fears

Psilocybin mushrooms (36.4%, χ² = 57.68, p < 0.01)

LSD (20.6%, χ² = 36.56, p < 0.01)

Ayahuasca (11.6%, χ² = 37.65, p < 0.01)

Synthetic DMT (7.9%, χ² = 34.70, p < 0.01)

DMT-Tepezcohuite (5%, χ² = 40.57, p < 0.01)

Floripondium (2.1%, χ² = 34.80, p < 0.01)

Distancing from people with whom I used to share frequently, without discomfort

Psilocybin mushrooms (22.3%, χ² = 44.51, p < 0.01)

Ayahuasca (24%, χ² = 46.07, p < 0.01)

San Pedro cactus (16.3%, χ² = 42.43, p < 0.01)

Peyote (10.8%, χ² = 31.79, p < 0.01)

DMT-Tepezcohuite (9.9%, χ² = 50.98, p < 0.01)

Synthetic DMT (4.7%, χ² = 35.11, p < 0.01)

Increased creativity

San Pedro cactus (14.5%, χ² = 44.62, p < 0.01)

Peyote (5.3%, χ² = 42.09, p < 0.01)

Physical well-being

San Pedro cactus (8.7%, χ² = 43.33, p < 0.01)

Peyote (8.2%, χ² = 38.96, p < 0.01)

Ayahuasca (7.9%, χ² = 42.56, p < 0.01)

Synthetic DMT (6.6%, χ² = 35.56, p < 0.01)

DMT-Tepezcohuite (3.3%, χ² = 41.83, p < 0.01)

Floripondium (2.1%, χ² = 35.93, p < 0.01)