Table 3 Relationship between RFM and incident diabetes in different models.

From: Non-linear relationship between relative fat mass and diabetes risk in Japanese adults: a retrospective cohort study

 

Variable

Model 1 (HR,95%CI, P)

Model 2 (HR,95% CI, P)

Model 3 (HR,95% CI, P)

All

RFM

1.24 (1.21, 1.27) < 0.0001

1.13 (1.08, 1.19) < 0.0001

1.08 (1.02, 1.14) 0.0055

 

RFM (quartile)

   
 

Q1

ref

ref

ref

 

Q2

2.01 (1.46, 2.76) < 0.0001

0.98 (0.69, 1.38) 0.9003

0.72 (0.51, 1.03) 0.0719

 

Q3

5.19 (3.79, 7.11) < 0.0001

1.32 (0.87, 2.00) 0.1972

0.96 (0.63, 1.47) 0.8539

 

Q4

19.03 (12.27, 29.53) < 0.0001

1.65 (0.84, 3.25) 0.1484

1.18 (0.58, 2.39) 0.6543

 

P for trend

< 0.0001

0.1033

0.6038

Female

RFM

1.28 (1.22, 1.33) < 0.0001

1.19 (1.09, 1.30) < 0.0001

1.13 (1.04, 1.24) 0.0061

 

RFM (quartile)

   
 

Q1

ref

ref

ref

 

Q2

2.11 (0.76, 5.81) 0.1502

1.40 (0.50, 3.90) 0.5190

1.34 (0.48, 3.75) 0.5814

 

Q3

3.59 (1.39, 9.29) 0.0084

1.61 (0.60, 4.29) 0.3442

1.28 (0.47, 3.49) 0.6335

 

Q4

14.42 (6.17, 33.68) < 0.0001

2.86 (1.04, 7.88) 0.0419

1.63 (0.56, 4.72) 0.3711

 

P for trend

< 0.0001

0.0240

0.3942

Male

RFM

1.22 (1.18, 1.26) < 0.0001

1.11 (1.04, 1.18) 0.0023

1.05 (0.98, 1.13) 0.1511

 

RFM (quartile)

   
 

Q1

ref

ref

ref

 

Q2

1.40 (0.86, 2.30) 0.1791

0.96 (0.58, 1.60) 0.8867

0.60 (0.36, 1.01) 0.0547

 

Q3

1.99 (1.26, 3.15) 0.0034

0.97 (0.59, 1.59) 0.9002

0.50 (0.30, 0.85) 0.0107

 

Q4

6.09 (4.05, 9.15) < 0.0001

1.76 (1.04, 3.00) 0.0367

0.82 (0.47, 1.46) 0.5031

 

P for trend

< 0.0001

0.0085

0.7088

  1. Model 1: we did not adjust for any covariants.
  2. Model 2: we adjusted for gender, age, BMI, alcoholic intake, smoking status, exercise habits, SBP, and DBP.
  3. Model 3: we adjusted for gender, age, BMI, alcoholic intake, smoking status, exercise habits, SBP, DBP, ALT, AST, GGT, HDL-C, TC, TG, HbA1c, and FPG.
  4. Note: The models were not adjusted for gender variables in both male and female models.
  5. HR: hazard ratio; CI: confidence interval; Ref: Reference; RFM: relative fat mass.