Fig. 4
From: Dendrite injury triggers neuroprotection in Drosophila models of neurodegenerative disease
Axotomy, terminal branch injury, and near branch injury do not induce neuroprotection. (A) Schematic of uninjured neurons (purple, UI), axotomized neurons (yellow), terminal branch injured neurons (orange, TermBI), and neurons left uninjured but exposed to an injury near a dendrite branch (red, NBI). Red arrows represent 2 photon laser injury. (B) Uninjured and axotomized WT, ATX1.82Q, and MJD.78Q overexpression neurons at 24 and 72 h after injury. Scale bar 50 μm. (C) Number of branch tips and total branch length between UI and axotomy at 72 h after injury. Welch’s t-test. (D) Uninjured and terminal branch injured neurons at 72 h after injury. Scale bar 50 μm. (E) Number of branch tips and total branch length between UI and TermBI at 72 h after injury. Welch’s t-test. (F) Uninjured and uninjured but exposed to a near branch injury neurons at 72 h after injury. Scale bar 50 μm. (G) Number of branch tips and total branch length between UI and NBI at 72 h after injury. Welch’s t-test. See also Fig S9.
