Table 3 Association of stroke with OSA and hypertension by rs6843082.
From: Obstructive sleep apnea and genotype rs6843082 as a risk factor for cerebrovascular accident
rs6843082(GG) | rs6843082(GA + AA) | |||
|---|---|---|---|---|
OR | 95% CI | OR | 95% CI | |
OSA (ref: No) | ||||
Yes | 2.31 | 1.60 - 3.36 | 1.98 | 1.24 - 3.16 |
Hypertension (ref: No) | ||||
Yes | 2.46 | 2.01 - 3.02 | 2.42 | 1.92 - 3.07 |
ZFHX3-rs7193343 (ref: TT) | ||||
TC + CC | 0.97 | 0.82 - 1.16 | 1.00 | 0.82 - 1.23 |
Sex (ref: Female) | ||||
Male | 1.05 | 0.84 - 1.29 | 1.07 | 0.84 - 1.37 |
Age (ref:30–50) | ||||
50–70 | 2.54 | 1.99 - 3.25 | 3.97 | 2.91 - 5.40 |
Education (ref: Elementary school) | ||||
Junior and Senior high school | 0.91 | 0.69 - 1.20 | 0.91 | 0.64 - 1.28 |
University above | 0.70 | 0.52 - 0.94 | 0.80 | 0.56 - 1.15 |
Smoke (ref: No) | ||||
Yes | 0.96 | 0.76 - 1.22 | 0.86 | 0.65 - 1.13 |
Alcohol drink (ref: No) | ||||
Yes | 1.27 | 0.96 - 1.67 | 1.12 | 0.80 - 1.57 |
Second-hand smoke (ref: No) | ||||
Yes | 0.74 | 0.54 - 1.02 | 1.04 | 0.73 - 1.47 |
Physical activity (ref: No) | ||||
Yes | 1.31 | 1.09 - 1.57 | 0.91 | 0.74 - 1.13 |
BMI | 1.02 | 0.99 - 1.05 | 0.95 | 0.92 - 0.98 |
Diabetes (ref: No) | ||||
Yes | 1.37 | 1.11 - 1.69 | 1.71 | 1.35 - 2.16 |
Hyperlipidemia (ref: No) | ||||
Yes | 1.61 | 1.32 - 1.98 | 1.76 | 1.39 - 2.24 |
Atrial fibrillation (ref: No) | ||||
Yes | 2.98 | 1.70 - 5.22 | 3.38 | 1.50 - 7.59 |
