Fig. 2

Multivariate analysis of pS6 and clinicopathological parameters as prognostic factors for RFS. Forest plots show the results obtained with pS6 and co-variables including (a) age (with less than 50 years as reference), (b) tumor size (with less than 2 cm as reference), (c) lymph node (LN) status (with negative LN as reference), and (d) stage (with stage I as reference). HR: hazard ratio; 95% CI: 95% confidence interval. Statistical significance was set at *p < 0.05.