Table 1 Patient characteristics.
| Â | Distribution | Missing, n (%) |
|---|---|---|
Age at diagnosis, median (range) | 56 (35–68) | 0 |
Tumor grade, n (%) | 312 | 1 (0.3) |
 1 | 98 (31.4) |  |
 2 | 132 (42.3) |  |
 3 | 82 (26.3) |  |
Molecular subgroup, n (%) | 312 | 1 (0.3) |
 Luminal A | 194 (62.2) |  |
 Luminal B | 63 (20.2) |  |
 HER2 +  | 15 (4.8) |  |
 Basal-like | 40 (12.8) |  |
Tumor diameter in millimeters, median (range) | 16 (1–92) | 0 |
Surgery, n (%) | 313 | 0 |
 Lumpectomy | 213 (68.1) |  |
 Mastectomy | 100 (32.0) |  |
Lymph node metastasis, n (%) | 311 | 2 (0.6) |
 Yes | 94 (30.2) |  |
 No | 217 (69.8) |  |
Distant metastasisa, n (%) | 310 | 3 (1.0) |
 Yes | 34 (11.0) |  |
 No | 276 (89.0) |  |
Relapse, n (%) | 311 | 2 (0.6) |
 Yes | 25 (8.0) |  |
 No | 286 (92.0) |  |
ER positive, n (%) | 313 | 0 |
 Yes | 253 (80.8) |  |
 No | 60 (19.2) |  |
PR positive, n (%) | 303 | 10 (3.2) |
 Yes | 203 (67.0) |  |
 No | 100 (33.0) |  |
HER2 positive, n (%) | 312 | 1 (0.3) |
 Yes | 38 (12.2) |  |
 No | 274 (87.8) |  |
Menopausal status at diagnosis | 313 | 0 |
 Post-menopausal | 219 (70.0) |  |
 Pre-menopausal | 94 (30.0) |  |
Age at menarche, mean (SD) | 13.0 (1.3) | 4 (1.3) |
Parity | 313 | 0 |
 0 | 32 (10.2) |  |
 ≥ 1 | 281 (89.8) |  |
Body mass index, n (%) | 306 | 7 (2.2) |
 < 25 | 182 (59.5) |  |
 25–30 | 95 (31.1) |  |
 > 30 | 29 (9.5) |  |
Smoking status at first questionnaire, n (%) | 312 | 2 (0.6) |
 Never | 108 (34.6) |  |
 Ever | 204 (65.4) |  |
