Table 5 Logistic regression analysis of the association between mir-20a-5p expression levels in stroma, in relation to clinicopathological parameters and breast cancer risk factors.

From: Roles of miR-20a-5p in breast cancer based on the clinical and multi-omic (CAMO) cohort and in vitro studies

 

N

Odds ratio

95% Confidence interval

p-value

Tumor size

309

0.90

0.67–1.20

0.48

Tumor grade

 1

97

Ref

Ref

Ref

 2

129

1.22

0.56–2.66

0.61

 3

82

1.59

0.70–3.61

0.27

Molecular subgroup

 Luminal A

191

Ref

Ref

Ref

 Luminal B

63

1.20

0.54–2.64

0.66

 HER2-enriched

15

0.98

0.21–4.58

0.98

 Basal like

39

1.64

0.68–3.95

0.27

Estrogen receptor

 Negative

59

Ref

Ref

Ref

 Positive

250

0.82

0.38–1.77

0.62

Progesterone receptor

 Negative

97

Ref

Ref

Ref

 Positive

202

0.92

0.47–1.80

0.80

HER2

 Negative

270

Ref

Ref

Ref

 Positive

38

1.08

0.42–2.74

0.88

Ki67

 Low

173

Ref

Ref

Ref

 High

87

2.02

1.02–4.01

0.043

Lymph node metastasis

 No

215

Ref

Ref

Ref

 Yes

92

1.30

0.67–2.52

0.44

Distant metastasisa

 No

273

Ref

Ref

Ref

 Yes

33

1.04

0.38–2.85

0.94

Relapse

 No

282

Ref

Ref

Ref

 Yes

25

3.02

1.22–7.49

0.017

Menopausal statusb

 Post

217

Ref

Ref

Ref

 Pre

92

2.81

1.48–5.33

0.002

BMI

 Low

274

Ref

Ref

Ref

 High

28

0.41

0.09–1.81

0.24

Parity

 Nulliparous

31

Ref

Ref

Ref

 Parous

278

1.20

0.40–3.61

0.74

Oral contraceptives

 Never

114

Ref

Ref

Ref

 Ever

184

0.74

0.39–1.40

0.36

Alcohol consumption

302

0.99

0.92–1.07

0.76

Smoking

 Never

106

Ref

Ref

Ref

 Ever

202

1.24

0.63–2.44

0.54

  1. HER2 Human epidermal growth factor receptor 2. aAt any time, bAt diagnosis.