Fig. 2

Genome-wide comparison of gene vulnerability, genetic diversity and species conservation–(A) Histogram of genes per percentage of polymorphic positions. Insert shows direct comparison between genes predicted to be essential verses non-essential. (B) Comparison of genetic diversity (% of positions that are completely conserved amongst all isolates) and gene vulnerability score⁸. (C) Comparison of genetic diversity and species conservation (between mycobacterium species). (D) Comparison of gene vulnerability score and species conservation. Genes are colour-coded based on essentiality.