Fig. 3 | Scientific Reports

Fig. 3

From: An open-access dashboard to interrogate the genetic diversity of Mycobacterium tuberculosis clinical isolates

Fig. 3

Genetic diversity of next generation drug targets in current development–Gene-wide genetic variation in (A) MmpL3, (B) LeuS, (C) DprE1 and (D) QcrB. See Supplemental Figs. S1 and S2 for sequence alignment and predicted drug binding regions for LeuS and DprE1. Inserts include regions predicted to interact with inhibitors and where mutations have been identified from lab-adapted resistance strains.

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