Fig. 6

The protein expression levels of (a) insulin receptor substrate (IRS-1), (b) endothelial nitric oxide synthase (eNOS), (c) protein kinase B (Akt), (d) representative Western blot images of proteins. Each bar represents at least six rats. C: Control; F: Fructose; M: Metformin; F + M: Fructose + Metformin. *p < 0.05, significantly different from C group; # p < 0.05, significantly different from F group; &p < 0.05, significantly different from M group.