Fig. 5 | Scientific Reports

Fig. 5

From: An innovative electrical neurostimulation approach to mimic reflexive urination control in spinal cord injury models

Fig. 5

Coordinated electrical stimulation of MPG and PN enhances urinary efficiency in SCI mice. (A) Example of voiding spots deposited in sham mice (left). Example of voiding spots deposited in SCI mice (middle). Examples of voiding spots induced by combined electrical stimulation of the PN and the MPG in SCI mice (right, Stimulation group, Stim). (B) Quantification of the voiding spot diameters in each group, two peripheral nerve sites, TPNS. n = 9 mice for each group. Student’s t-test (two-tailed, unpaired). ***p < 0.001. (C,D) Representative IVP trace (top) and time-locked EUS-EMG signal (bottom). Each non-voiding or voiding event is denoted by arrows or asterisks. (E,F) Enlarged view of the dashed line boxes in panel (C,D).

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