Table 1 Subject characteristics from cohorts 1 and 2.

From: Cystic fibrosis-related diabetes is associated with reduced islet protein expression of GLP-1 receptor and perturbation of cell-specific transcriptional programs

 

N

Age

(years)

Sex

(female/

male)

BMI

(kg/m2)

Diabetes duration

(years)

HbA1c

(%)

Cohort 1:

Autopsy tissue from Seattle Children’s Hospital and University of Washington Medical Center

Control

9

16.6±10.1

6/3

20.8±7.1 [N = 7]

-

-

CF

10

15.6±8.0

7/3

17.9±4.3 [N = 9]

-

-

CFRD

9

26.4±8.8*

5/4

22.8±2.8

4.3±3.7

7.3±2.1 [N = 7]

Cohort 2:

Organ donor tissue from Network for Pancreatic Organ Donors with Diabetes

Control

6

26.7±5.0

4/2

24.9±3.4

-

-

CFRD

5

27.1±5.9

4/1

19.7±2.1*

3.6±3.0 [N = 4]

6.6±0.7 [N = 4]

  1. Data are mean ± SD or N. *p < 0.01 vs. Control