Table 1 Correlation between presence of the PIK3CA (H1047R) mutation and other clinical parameters.

From: Detection of PIK3CA hotspot mutations in canine mammary tumors using droplet digital PCR: tissue validation and liquid biopsy feasibility

 

Number of samples (%)

 

PIK3CA (H1047R)

P value

Positive

Negative

Neuter status

 Intact female (n = 49)

19 (38.8%)

30 (61.2%)

0.170a

 Spayed female (n = 26)

6 (23.1%)

20 (76.9%)

 

Histological subtype

 Simple type (n = 40)

13 (32.5%)

27 (67.5%)

0.719a

 Complex type (n = 30)

9 (30%)

21 (70%)

 

 Mixed type (n = 9)

4 (44.4%)

5 (55.6%)

 

Histological grade

 Grade I (n = 41)

17 (41.5%)

24 (58.5%)

0.079b

 Grade II (n = 13)

2 (15.4%)

11 (84.6%)

 

 Grade III (n = 14)

2 (14.3%)

12 (85.7%)

 

Histological grade

 Benign and Grade I (n = 53)

22 (41.5%)

31 (58.5%)

0.016a

 Grade II and Grade III (n = 27)

4 (14.8%)

23 (85.2%)

 

Lymphatic invasion

 Absent (n = 73)

25 (34.2%)

48 (65.8%)

0.418b

 Present (n = 7)

1 (14.3%)

6 (85.7%)

 
  1. aChi-square test.
  2. bFisher’s exact test.
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