Fig. 1

Kidney cells present hIAPP aggregates after incubation with CM from INS1E-hIAPP during 8 and 24 h. A, B, C: Immunofluorescence staining of podocyte, mesangial and tubular cells, respectively. Aggregates were detected with MG5 compound (green signal) and cell nuclei with DAPI (blue). The plot indicates the mean and standard deviation, n (independent studies) = 3. * p < 0,05; **: p < 0,01; ***p < 0,005, **** p < 0,0005.