Fig. 2 | Scientific Reports

Fig. 2

From: Identification of diagnostic markers pyrodeath-related genes in non-alcoholic fatty liver disease based on machine learning and experiment validation

Fig. 2

Identification of DE-PRGs in NAFLD. (A) Volcano plot of DEGs between NAFLD and control samples. (B) Heatmaps of the top 50 genes are presented. The top 50 genes included the top 25 DEGs with the largest values for positive logFC and the top 25 DEGs with the largest absolute values for negative logFC. (C) Venn diagrams showing the intersection between DEGs and PRGs. (D) Ten DE-PRGs are presented with the boxplots illustrating the differential expression between NAFLD and control samples. (E) Heatmap showing the expression patterns of these 10 DE-PRGs. P values are displayed as follows: *p < 0.05; **p < 0.01; ***p < 0.001. DEGs differentially expressed genes, DE-PRGs differentially expressed pyroptosis-related genes, PRGs pyroptosis-related genes, NAFLD nonalcoholic fatty liver disease.

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