Table 1 Patient characteristics at the time of surgical lung biopsies, and their outcomes (n = 3 in each group).
From: Spatially resolved gene expression profiles of fibrosing interstitial lung diseases
IPF | NSIP | CHP | Unclassifiable | P value | Normal controls | |
|---|---|---|---|---|---|---|
Age | 69 ± 9 | 37 ± 21 | 71 ± 10 | 52 ± 3 | 0.0320a | 46 ± 20 |
Gender | M/M/F | M/F/F | F/F/F | M/F/F | n.s | M/M/M |
BMI (kg/m2) | 30 ± 6 | 26 ± 6 | 34 ± 6 | 37 ± 2 | n.s | 25 ± 5 |
Smoking history (pack-years) | 7 ± 12 | 16 ± 27 | 0 ± 0 | 7 ± 12 | n.s | 10 ± 17 |
FVC (% pred) | 63 ± 15 | 69 ± 29 | 67 ± 3 | 57 ± 28 | n.s | N/A |
TLC (% pred) | 66 ± 10 | 71 ± 27 | 63 ± 9 | 59 ± 21 | n.s | N/A |
DLCO (% pred) | 49 ± 3 | 41 ± 23 | 52 ± 22 | 67b | n.s | N/A |
6MWD (m) | 405 ± 69 | 430 ± 163 | 356 ± 78 | 331 ± 244 | n.s | N/A |
Alive/dead/LTx | 2/1/0 | 2/0/1 | 3/0/0 | 1/2/0 | n.s | 3/0/0 |
Post-biopsy survival (months) | 20 ± 9 | 22 ± 4 | 33 ± 15 | 23 ± 13 | n.s | 37 ± 7 |
