Table 1 Distribution of Qs-FQs resistance phenotype amongst the Ecoli isolates and impact of asssociated molecular mechanisms on MICs.

From: Molecular mechanisms impact on fluoroquinolone resistance among E.coli from enteric carriage monitoring before prostate biopsy and earliest description of qnrB81

Resistance phenotype

(N-%)

Qs MICs (mg/L)

FQs MICs (mg/L)

QRDRs mutations

PMQRs gene

NAL

S ≤ 16 R > 16

OFX

S ≤ 0,25 R > 0,5

CIP

S ≤ 0,25 R > 0,5

Total number

gyrA

parC

Profile I

6 (7,50%)

24

R

0,24

S

0,24

S

-

-

-

1

Profile II

9 (11,25%)

256<

R

0,5

I

0,24

S

1

1

-

-

Profile III

65 (81,25%)

9 (11,25%)

256<

R

2–4

R

1–4

R

2

1

1

-

10 (12,5%)

256<

R

1–64

R

1–32

R

1

1

-

1

26 (32,5%)

256<

R

8–32

R

8–32

R

2

2

-

-

16 (20%)

256<

R

8–64

R

8–64

R

3

2

1

-

4 (5%)

256<

R

64–128

R

64–128

R

4

2

2

-

  1. PMQRs: plasmid resistance to fluoroquinolones, QRDRs: quinolone resistance determining regions MICs: Minimum inhibitory concentrations NA : Nalidixic acid; OFX, ofloxacine CIP, Ciprofloxacin,, S : Sensitive ; I : Intermediat ; R :Resistant.