Table 3 Characterization of E. coli isolates grouped on Profil I in terms of phenotypic resistance and its genotypic basis, phylogenetic groups, and clonal relatedness.
Strains | Qs -FQs resistance phenotypes NAL NXN OFX CIP | Qs-FQs MICs (mg/L) | ATB resistance profiles | QRDRs mutations | PMQRs gene | Phylogenetic group | ST131 clone | PFGE pulsotype/subtype | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NAL S ≤ 16 R > 16 | OFX S ≤ 0.25 R > 0.5 | C.I.P. S ≤ 0.25 R > 0.5 | ß-lactams | Aminoglycosides | Other | gyrA | parC | ||||||
E. coli (1) | RSSS | 24 | 0.24 | 0.24 | AMP, TIC, PIP | - | - | WP | WP | qnrS1 | B2 | + | Pulsotype I |
E. coli (2) | RSSS | 24 | 0.24 | 0.24 | AMP, TIC, PIP | - | - | WP | WP | qnrS1 | B2 | + | Pulsotype I |
E.coli (3) | RSSS | 24 | 0.24 | 0.24 | AMP, TIC, PIP | - | CHL, SXT | WP | WP | qnrB19 | Unknown | - | - |
E. coli (4) | RSSS | 24 | 0.24 | 0.24 | AMP, TIC, PIP, AMC, TCC, MEC | - | - | WP | WP | qnrB81 | Clade I or II | - | - |
E.coli (5) | RSSS | 24 | 0.24 | 0.24 | AMP, TIC, PIP | - | SXT | WP | WP | qnrB | B2 | + | Pulsotype VII |
E.coli (6) | RSSS | 24 | 0.24 | 0.24 | AMP, TIC, PIP | - | SXT | WP | WP | qnrS15 | B2 | + | Subtype VIIIb |