Table 4 Characterization of E. coli isolates grouped on profil II in terms of phenotypic resistance and its genotypic basis, phylogenetic groups, and clonal relatedness.
Strains | Qs-FQs resistance phenotypes NAL NXN OFX CIP | Qs -FQs MICs (mg/L) | ATB resistance profiles | QRDRs mutations | PMQRs gene | Phylogenetic group | ST131 clone | PFGE pulsotype/subtype | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NAL S≤16 R>16 | OFX S≤0.25 R>0.5 | C.I.P. S≤0.25 R>0.5 | ß-lactams | Aminoglycosides | Other | gyrA | parC | ||||||
E. coli (7) | RSSS | 256 | 0.5 | 0.24 | AMP, TIC, PIP | - | - | S83L | WP | - | B2 | - | - |
E.coli (8) | RSSS | 256 | 0.5 | 0.24 | AMP, TIC, PIP | - | SXT | S83T | WP | - | B2 | - | - |
E. coli (9) | RSSS | 256 | 0.5 | 0.24 | - | - | SXT | S83L | WP | - | Clade I or II | - | - |
E.coli (10) | RSSS | 256 | 0.5 | 0.24 | AMP, TIC, PIP | - | - | S83L | WP | - | B2 | - | - |
E. coli (11) | RSSS | 256 | 0.5 | 0.24 | AMP, TIC, PIP | - | CHL, SXT | S83L | WP | - | B2 | - | - |
E.coli (12) | RSSS | 256 | 0.5 | 0.24 | - | - | - | D87N | WP | - | B2 | + | Pulsotype VI |
E.coli (13) | RSSS | 256 | 0.5 | 0.24 | - | - | - | D87N | WP | - | Unknown | - | - |
E.coli (14) | RSSS | 256 | 0.5 | 0.24 | MEC | - | - | S83L | WP | - | Clade I or II | - | - |
E. coli (15) | RSSS | 256 | 0.5 | 0.24 | AMP, TIC, PIP | - | SXT | S83L | WP | - | Clade I or II | - | - |