Table 3 Tolerance experiment of Heyndrickxia coagulans BC99.

From: Comprehensive genomic analysis and evaluation of in vivo and in vitro safety of Heyndrickxia coagulans BC99

Reagent

pH

lg CFU/mL

Bacterial survival rate /%

0 h

2 h

MRS

2.5

6.84 ± 0.06

6.77 ± 0.05

97.45

3.0

6.69 ± 0.04

6.72 ± 0.02

98.95

3.5

8.78 ± 0.02

8.77 ± 0.03

99.83

Simulated gastric fluid

2.5

6.80 ± 0.04

6.62 ± 0.03

97.44

3.0

6.95 ± 0.05

6.720 ± 0.02

96.73

3.5

8.81 ± 0.03

8.80 ± 0.02

99.88

Simulated intestinal fluid

6.8

8.84 ± 0.06

8.82 ± 0.05

99.74

Bile salt

6.9

8.14 ± 0.01

7.56 ± 0.00

92.85

  1. ‘lg CFU/mL’ refers to the logarithmic value (base 10) of colony-forming units per milliliter, used to standardize microbial counts for comparative analysis.
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