Table 1 Summarizing data regarding lesion type, histopathological diagnosis, and protein expression.
Experimental groups | Macroscopy lesion type at the end of the experiment | Histopathological diagnosis | Mean immunoreactive score (min-max) | ||
|---|---|---|---|---|---|
p53 | ROS1 | ||||
12 weeks | Control | - Areas of white spot/plaque with a smooth surface = 4 - White plaques with an irregular surface = 7 | - Epithelial dysplasia = 7 - In situ carcinoma = 4 | 8.1 (3–15) | 7.1 (1–15) |
PBM 0.3 J | - Areas of white spot/plaque with a smooth surface = 1 - White plaques with an irregular surface = 10 | - Epithelial dysplasia = 8 - In situ carcinoma = 3 | 6.5 (3–12) | 8 (2–12) | |
PBM 1 J | - Areas of white spot/plaque with a smooth surface = 1 - White plaques with an irregular surface = 5 - Nodular areas = 5 | - Hyperplasia, acanthosis and hyperkeratosis = 2 - Epithelial dysplasia = 6 - In situ carcinoma = 3 | 6.6 (3–10) | 8.5 (0–15) | |
20 weeks | Control | - White plaques with an irregular surface = 2 - Nodular areas = 7 - Ulcer = 2 | - Epithelial dysplasia = 1 - In situ carcinoma = 1 - OSCC = 9 | 8.5 (5–15) | 11.9 (6–15) |
PBM 0.3 J | - White plaques with an irregular surface = 2 - Nodular areas = 6 - Ulcer = 3 | - Epithelial dysplasia = 1 - In situ carcinoma = 1 - OSCC = 9 | 7.8 (2–10) | 11.3 (6–15) | |
PBM 1 J | - White plaques with an irregular surface = 2 - Nodular areas = 5 - Ulcer = 5 | - Epithelial dysplasia = 3 - In situ carcinoma = 2 - OSCC = 6 | 8.1 (2–12) | 11.4 (8–15) | |
