Table 3 Reporting serious adverse events (SAEs) and other adverse events (OAEs) for glaucoma trials (n = 79) in ClinicalTrials.gov and the publications.

From: Safety reporting in trials on glaucoma interventions registered in ClinicalTrials.gov and corresponding publications

 

No. (%)

Different number of patients with SAEs

 

  Yes

16 (20)

  No

49 (62)

  Othera

14 (18)

If different number of patients with SAEs (n = 16)

 

  More in the register

11 (69)

  More in the publication

5 (31)

Different absolute number of different SAE

 

  Yes

19 (24)

  No

38 (48)

  Otherb

22 (28)

If different number of different SAEs

 

  More in register

14 (74)

  More in publication

5 (26)

Different description of SAEs

 

  Yes

14 (18)

  No

30 (38)

  Otherc

35 (44)

Description omitted in publication for 1 or more registered SAEs

 

  Yes

26 (33)

  No

45 (57.0)

  Otherd

8 (10.1)

Total

79(100.0)

  1. Abbreviations: SAE – serious adverse events, n/c – not categorized,
  2. aBecause of missing information in the publication (n = 14).
  3. bBecause of missing information in the publication (n = 22).
  4. cBecause of zero SAEs reported (n = 19) and/or missing information in the publication (n = 16).
  5. dReported as zero in the registry, and not mentioned in the publication.
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