Fig. 4 | Scientific Reports

Fig. 4

From: Synthesis of potent vasodilating agents: in silico and in vitro evaluation of 6-(4-substitutedphenyl)-3-pyridazinone derivatives as potential hydralazine analogues

Fig. 4

Dose response curve with the mean EC50 for compounds; (a): Nitroglycerin, (b):2e compound (c): 2h, (d): 2j and (e): Mean EC50. Values represent means ± SD (n = 5rats for each investigated drug). A significant difference is reported when P is less than 0.05 and determined by one -way ANOVA followed by pairwise comparison using Dunnet ’s test. ****statistically significant as compared to the nitroglycerin control group (P˂0.0001).

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