Table 1 The ten generated hypotheses with their maximum fit, total cost, cost difference, RMS and correlation coefficient.

From: Synthesis of potent vasodilating agents: in silico and in vitro evaluation of 6-(4-substitutedphenyl)-3-pyridazinone derivatives as potential hydralazine analogues

Hypothesis

Maximum fit

Total cost

Cost difference

RMS

Correlation coefficient

1

6.699

78.203

62.030

2.390

0.813

2

7.330

87.920

52.312

2.662

0.761

3

5.439

91.703

48.530

2.793

0.732

4

4.646

105.191

35.042

3.12

0.649

5

4.916

106.755

33.478

3.168

0.635

6

4.275

110.204

30.029

3.225

0.619

7

5.166

111.228

29.005

3.248

0.614

8

3.937

111.301

28.932

3.232

0.616

9

4.581

112.050

28.182

3.282

0.600

10

4.127

121.294

18.939

3.472

0.534

Back to article page