Fig. 3
From: A comparison of cognitive decline in aged mice and mice treated with aftin-4
Behavior of all the groups in the three-chamber sociability test. (A) Schematic representation of the first socialization phase. (B) Time spent sniffing the empty box by the animals during the first phase. The animals in the aged group spent less time exploring the empty box than did the animals in the control group. **P < 0.01 aged mice vs. the control group by two-way ANOVA followed by Tukey’s post hoc analysis. (C) SI. No real difference was found between the mean values, although the mean SI tended to be greater in aged animals (p = 0.05). (D) Schematic representation of the second phase, the social novelty preference phase. (E) No difference was found between the groups in terms of the SNI. The data are presented as the means ± SDs, except for the SNI data (shown as medians and interquartile ranges). Aftin-4 group (n = 11 females, 12 males), control group (n = 12 females, 12 males), and aged group (n = 11 females, 10 males).
