Fig. 9

mRNA expression levels of VEGFA, MYC, and JUN in the synovial tissues of OA patients and healthy controls, and their correlation with OA severity. (A-C) Relative mRNA expression levels of (A) VEGFA, (B) MYC, and (C) JUN in synovial tissues from 20 OA patients and 10 healthy controls. (D–F) mRNA expression levels of VEGFA, MYC, and JUN in synovial tissues of patients with varying Kellgren-Lawrence (K–L) scores. (G–I) mRNA expression levels of VEGFA, MYC, and JUN in synovial tissues of patients with different durations of pain. Data are presented as mean ± SD, with statistical significance between normal and OA groups calculated using the Student’s t-test. Significance statistics for Kellgren-Lawrence scores and durations of pain using ANOVA. *p < 0.05; **p < 0.01; ***p < 0.001.