Table 1 The demographic and clinical characteristics of the subjects.

From: Transcriptomic profiling and machine learning reveal novel RNA signatures for enhanced molecular characterization of Hashimoto’s thyroiditis

Parameters

Controls

HT cases

P-value

Gender (Female)

28(93%)

31(100%)

0.458

Marital status (Married)

26(87%)

25(81%)

0.772

Age (Y)

41.8 ± 13.6

42.1 ± 12.2

0.921

Weight (kg)

59.2 ± 7.6

60.1 ± 9.6

0.705

Thyroid volume (cm3)

0.2 ± 0.0

0.3 ± 0.1

3.95E-05

SWE (KPa)

14.3 ± 5.2

43.3 ± 10.0

1.11E-20

FT3 (pmol/l)*

3.7 ± 0.6

4.3 ± 0.8

1.10E-03

FT4 (pmol/l)*

14.2 ± 1.7

16.6 ± 2.6

9.02E-05

TSH (µIU/ml)*

1.7 ± 1.1

5.0 ± 0.8

3.17E-20

TPO-Ab (IU/ml)*

11.9 ± 7.6

568.4 ± 294.9

7.50E-15

TG-Ab (IU/ml)*

31.9 ± 25.4

697.8 ± 270.2

1.32E-19

  1. Fisher’s exact tests were utilized for categorical variables, such as gender and marital status. For continuous variables, t-tests were employed. If the variances are unequal, Welch’s t-test was used instead. Significant values are in bold.
  2. HT: Hashimoto thyroiditis, SD: Standard Deviation. Data are shown as mean ± SD.
  3. *The normal value ranges of the five biochemical indicators FT3, FT4, TSH, TPOAb, and TGAb in the sample recruitment hospitals are as follows: FT3 (3.0-8.1), FT4 (12–22), TSH (0.3–4.5), TPOAb (0–34), and TGAb (0-115).
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