Fig. 3 | Scientific Reports

Fig. 3

From: Wogonin suppresses proliferation, invasion and migration in gastric cancer cells via targeting the JAK-STAT3 pathway

Fig. 3

Wogonin induces increased apoptosis and ROS of GC cells. (A) Flow cytometric analysis of apoptosis of SGC-7901 and BGC-823 cells exposed to wogonin at different concentrations for 48 h. (B) TUNEL analysis of apoptosis of SGC-7901 and BGC-823 cells treated with 90 µM wogonin for 48 h. (C) Western blotting analysis to detect the levels of apoptosis regulating proteins of SGC-7901 and BGC-823 cells exposed to wogonin at different concentrations for 48 h. (D) Mitochondrial membrane potential analysis of SGC-7901 and BGC-823 cells treated with wogonin at different concentrations for 48 h. (E) ROS levels in SGC-7901 and BGC-823 cells treated with wogonin for 48 h were presented through combination with DCFH-CA. *p < 0.05 vs. DMSO group, ***p < 0.001 vs. DMSO group.

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