Table 3 Significant correlations between chromosome aberrations, side effects, and RILA values over time.

From: Assessment of the predictive power the radiation-induced lymphocyte apoptosis method in prostate cancer patients

 

Before therapy

Directly after therapy

3 months

6 months

9 months

12 months

24 months

36 months

48 months

60 months

Acute GU side effects

 

chrom. br., dic., total a., ab.cell

dic.

  

dic.

    

Acute GI side effects

 

chrom. br.

  

total a.,ab. cell,

 

chrom. br.

 

chrom. br., ab.cell

 

Cumulative late GU side effects

         

total a., ab.cell

Cumulative late GI side effects

          

Acute IPSS score

 

dic., total a., ab.cell

        

Acute QoL score

 

chrom. br.

    

dic., total a., ab.cell

   

Late cumulative IPSS increase

  

chrom. br.

       

Late cumulative QoL increase

 

total a.

        

Late cumulative IPSS score

chrom. br., total a., ab.cell

chrom. br., total a.

chrom. br.

dic., ab.cell

 

dic.

 

total a., ab.cell

  

Late cumulative QoL score

 

chrom. br., total a.

 

dic.

      

RILA value (%)

  

chrom. br.

    

chrom. br.

  
  1. (GU: genitourinary side effects, GI: gastrointestinal side effects, IPSS: international prostate symptom score, QoL: quality of life, chrom. br.: chromatid breaks, total a.: total aberrations, dic.: dicentric + ring chromosomes, ab. Cell: aberrant cells).