Table 4 Multivariate regression models of side effects.

From: Assessment of the predictive power the radiation-induced lymphocyte apoptosis method in prostate cancer patients

 

Acute GU side effects

Cumulative late GU side effects

Acute IPSS score

Acute QoL score

Late cumulative IPSS increase

Late cumulative QoL increase

Late cumulative IPSS score

Late cumulative QoL score

Model p

< 0.0001

0.010

0.002

0.008

< 0.001

0.002

0.001

0.005

Adjusted R2 (%)

46.3

14.9

22.8

16.1

44.9

30.7

25.3

22.7

RILA value (%)

    

0.014

   

Smoking (yes/no)

0.044

0.010

  

0.003

   

Hormone therapy (yes/no)

     

0.048

 

0.035

Age

        

Risk (d’Amico)

        

Radiotherapy (Cyberknife /HDR)

< 0.0001

  

0.008

0.008

0.020

0.001

0.038

Initial questionnaire score

    

< 0.001

0.002

  

V10Gy (cm3)

  

0.002

     

Total aberrations (directly after RT)

        
  1. Baseline characteristics of the patients, treatments, RILA, and chromosome aberrations were introduced to the model. (GU: genitourinary side effects, GI: gastrointestinal side effects, IPSS: international prostate symptom score, QoL: quality of life, HDR: high dose rate Brachytherapy, RT: radiotherapy).
Back to article page