Table 2 TYR inhibition (IC50) results of BPPH ultrafiltered fractions.

From: Bee pollen peptides as potent tyrosinase inhibitors with anti-melanogenesis effects in murine b16f10 melanoma cells and zebrafish embryos

Molecular weight (kDa)

L-Tyrosine (mono-phenolase activity) IC50 (µg/mL)

L-DOPA (di-phenolase activity) IC50 (µg/mL)

> 10

60.15 ± 1.66c

66.83 ± 5.56c

10–5

12.60 ± 1.65b

12.58 ± 1.07b

5–3

3.52 ± 1.22a

5.33 ± 1.90a

3-0.65

2.34 ± 1.31a

4.01 ± 2.66a

< 0.65

1.08 ± 0.50a

1.82 ± 0.80a

  1. All values are presented in the form of TYR inhibition mean (IC50 value) ± SE. Deviation, with the tests performed in triplicate. When a letter in superscript is presented in the same column, this is showing significant differences (p > 0.05).
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