Fig. 5 | Scientific Reports

Fig. 5

From: Efficacy of graphene quantum dot-hyaluronic acid nanocomposites containing quinoline for target therapy against cancer cells

Fig. 5

Cytotoxic effects of GQD-HA-Qu NCs on various cancer cell lines. The MTT assay results show a concentration-dependent reduction in cell viability for MCF-7 (A), HT-29 (B), A2780 (C), PANC-1 (D), and HeLa (E) cells. A2780 cells exhibited the highest sensitivity, followed by HT-29, while MCF-7 cells demonstrated greater sensitivity than HT-29 at 250 µg/mL and 50 µg/mL and more sensitivity than A2780 at 500 µg/mL. In contrast, HeLa cells showed the highest resistance, maintaining significant viability, and PANC-1 cells displayed minimal response to lower concentrations, indicating a need for higher doses for an effective response. The data is presented as mean ± standard deviation (SD), and statistical significance is denoted as *** P < 0.001.

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