Table 2 Adjusted OR (95% CI) for the associations between phr and diabetes/prediabetes.

From: Platelet to high density lipoprotein cholesterol ratio is associated with diabetes and prediabetes in NHANES 2005 to 2018

PHR

Range

Model 1

Model 2

Model 3

Diabetes

Continuous

 

1.15 (1.12, 1.18)

1.14 (1.10, 1.18)

1.13 (1.09, 1.17)

Categories

Q1

< 3.51

1

1

1

Q2

3.51–4.56

1.39 (1.19, 1.61)

1.35 (1.09, 1.68)

1.32 (1.06, 1.64)

Q3

4.56–5.87

1.58 (1.36, 1.83)

1.46 (1.18, 1.82)

1.42 (1.14, 1.77)

Q4

> 5.87

2.27 (1.96, 2.62)

2.18 (1.74, 2.73)

2.08 (1.66, 2.61)

p-trend

 

< 0.01

< 0.01

< 0.01

Prediabetes

Continuous

 

1.09 (1.07, 1.12)

1.11 (1.08, 1.15)

1.18 (1.06, 1.32)

Categories

Q1

< 3.51

1

1

1

Q2

3.51–4.56

1.16 (1.03, 1.30)

1.29 (1.10, 1.51)

2.09 (1.38, 3.17)

Q3

4.56–5.87

1.30 (1.16, 1.46)

1.43 (1.21, 1.69)

2.38 (1.43, 3.98)

Q4

> 5.87

1.65 (1.47, 1.85)

1.79 (1.50, 2.12)

2.68 (1.61, 4.45)

p-trend

 

< 0.01

< 0.01

< 0.01

Diabetes and Prediabetes

Continuous

 

1.13 (1.11, 1.16)

1.13 (1.08, 1.16)

1.17 (1.05, 1.30)

Categories

Q1

< 3.51

1

1

1

Q2

3.51–4.56

1.21 (1.08, 1.35)

1.26 (1.09, 1.47)

1.89 (1.24, 2.87)

Q3

4.56–5.87

1.39 (1.25, 1.56)

1.44 (1.20, 1.68)

2.18 (1.30, 3.64)

Q4

> 5.87

1.93 (1.73, 2.16)

1.88 (1.60, 2.21)

2.55 (1.52, 4.28)

p-trend

 

< 0.01

< 0.01

< 0.01

  1. The PHR was categorized into four quartiles and tests for trend (p–trend) based on variable containing the median value for each quartiles. PHR also was utilized as continuous variables and p-value was used to test significance.
  2. Model 1 included only PHR as the independent variable. Model 2 included adjustments for sex, race, age, poverty status, smoking status, alcohol status, education, BMI, and physical activity. Model 3 built on Model 2 by further adjusting for hypertension, CVD, CKD, TG, LDL-C, hs-CRP, SUA and Cr.
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