Fig. 8

Expression levels of circulating miRNAs (miR-99b-5p, miR-101-3p, and miR-431-5p) in RA patients with and without a family history of the disease. The bar graphs depict the fold expression levels of three miRNAs in RA patients, comparing those with a family history of the disease to those without. miR-99b-5p (Left): Shows similar expression levels between patients with and without a family history of RA. miR-101-3p (Middle): Displays significantly higher expression in patients with a family history of the disease compared to those without, indicated by the asterisk (*), highlighting a significant statistical difference. miR-431-5p (Right): Indicates no significant difference in expression levels between the two groups.