Fig. 3
The predicted 3D structure of TsTGH2. (A) The 3D structure of full-length TsTGH2 was modelled and refined by I-TASSER and GalaxyRefine server using the crystal structure of Sus scrofa TGF- β1 (PDB ID: 3rjrA) as the template. (B) The 3D structure of mature-TsTGH2, consisting cysteine knot (indicated by a red circle) with two pairs of antiparallel β-strands (fingers) extending from wrist helix. Three intrachain disulfide bridges between cysteines are shown in stick format: C317–C388 (red stick), C346–C420 (yellow stick), and C350–C422 (green stick).
