Table 3 Comparison of FC among AD, MCI, and NC groups.

From: Resting-state functional magnetic resonance imaging study on cerebrovascular reactivity changes in the precuneus of Alzheimer’s disease and mild cognitive impairment patients

ROI

Cluster

Brain regions

Peak MNI coordinates

Peak intensity

P-value

X

Y

Z

PCUN.R

844

CC2.L

− 12

− 87

− 33

15.595

<0.001

783

DCG.R

12

− 42

36

17.1176

<0.001

220

ANG.L

− 48

− 66

24

12.8245

<0.001

178

MFG.L

− 27

30

45

15.5139

<0.001

102

MFG.R

33

33

48

11.0085

<0.001

PCUN.L

317

Cere8.L

− 42

− 54

− 51

13.1563

<0.001

87

Cere6.R

9

− 60

− 27

10.8644

<0.001

344

PCUN.R

9

− 45

18

13.4664

<0.001

168

SFGmed.R

3

42

39

11.2559

<0.001

  1. P-value were obtained by analysis of covariance adjusting for age, sex, education and head motion. FC functional connectivity, AD Alzheimer’s disease, MCI mild cognitive impairment, NC normal controls, ROI region of interest, MNI Montreal Neurological Institute, PCUN.R right precuneus, PCUN.L left precuneus, CC2.L left crus II of cerebellar hemisphere, DCG.R right middle cingulate and paracingulate gyri, ANG.L left angular gyrus, MFG.L left middle frontal gyrus, MFG.R right middle frontal gyrus, Cere8.L left lobule VIII of cerebellar hemisphere, Cere6.R right lobule VI of cerebellar hemisphere, SFGmed.R right Superior frontal gyrus, medial.
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