Table 1 Characteristics of the study population.

Age (years)

54.69 ± 11.68

51.95 ± 11.81

50.32 ± 11.74

48.06 ± 12.64

< 0.001

Nationality (%)

0.107

non-Han nationality

2(0.46%)

1(0.23%)

5(1.13%)

7(1.59%)

Han nationality

434(99.54%)

439(99.77%)

436(98.87%)

432(98.41%)

Marital status (%)

0.232

Not married

17(3.90%)

15(3.41%)

24(5.44%)

26(5.92%)

Married

419(96.10%)

425(96.59%)

417(94.56%)

413(94.08%)

BMI (kg/m²), (%)

< 0.001

< 24

233(53.44%)

166(37.73%)

111(25.17%)

68(15.49%)

≥ 24, < 28

180(41.28%)

212(48.18%)

258(58.50%)

245(55.81%)

≥ 28

23(5.28%)

62(14.09%)

72(16.33%)

126(28.70%)

SBP (mmHg)

130.49 ± 18.44

131.31 ± 17.12

129.70 ± 18.21

133.00 ± 18.61

0.046

DBP (mmHg)

77.33 ± 11.62

78.70 ± 10.73

78.71 ± 12.04

80.71 ± 12.25

< 0.001

TC (mmol/L)

4.96 ± 0.94

4.94 ± 0.99

4.83 ± 0.93

4.79 ± 1.00

0.019

TG (mmol/L)

1.22(0.92–1.63)

1.42(1.04–1.87)

1.73(1.27–2.29)

2.22(1.59–3.02)

< 0.001

LDL-C (mmol/L)

2.87 ± 0.81

3.04 ± 0.83

3.00 ± 0.75

2.99 ± 0.78

0.008

TP (g/L)

70.95 ± 4.00

71.29 ± 4.71

71.61 ± 3.95

71.73 ± 3.98

0.028

Hb (g/L)

150.18 ± 9.68

152.23 ± 10.37

152.70 ± 9.77

152.85 ± 10.59

< 0.001

TB (µmol/L)

14.29 ± 5.57

13.56 ± 5.30

13.50 ± 5.33

12.68 ± 5.29

< 0.001

ALT (U/L)

17.95(14.10–24.50)

19.85(14.97–28.65)

22.60(16.90–30.60)

25.10(18.10-35.95)

< 0.001

AST (U/L)

20.00(16.80–24.70)

20.10(16.80–24.10)

20.20(17.00-24.10)

20.70(17.35–25.50)

0.292

ALP (U/L)

66.51 ± 14.78

67.80 ± 17.43

67.80 ± 16.84

69.24 ± 17.79

0.155

GGT (U/L)

22.75(17.70-35.05)

25.90(19.50-36.95)

30.00(21.20–43.30)

32.10(22.90-48.45)

< 0.001

FBG (mmol/L)

5.16 ± 0.59

5.16 ± 0.55

5.24 ± 0.58

5.21 ± 0.59

0.088

Serum creatinine (µmol/L)

72.63 ± 10.00

74.96 ± 10.62

75.97 ± 12.14

77.77 ± 13.65

< 0.001

LFC (%)

7.25 ± 3.51

8.57 ± 4.44

9.47 ± 4.84

11.43 ± 5.80

< 0.001

Female (n= 1153)

UHR (%)

Q1(5.52–14.40)

Q2(14.41–17.96)

Q3(17.97–22.17)

Q4(22.27–43.13)

P value

Age (years)

51.07 ± 9.66

51.00 ± 10.14

52.56 ± 10.72

53.34 ± 9.93

0.011

Nationality (%)

0.789

non-Han nationality

5(1.74%)

5(1.75%)

6(2.08%)

3(1.03%)

Han nationality

283(98.26%)

281(98.25%)

282(97.92%)

288(98.97%)

Marital status (%)

0.214

Not married

10(3.47%)

13(4.55%)

7(2.43%)

5(1.72%)

Married

278(96.53%)

273(95.45%)

281(97.57%)

286(98.28%)

BMI (kg/m²), (%)

< 0.001

< 24

230(79.86%)

200(69.93%)

158(54.86%)

122(41.92%)

≥ 24, < 28

50(17.36%)

70(24.48%)

102(35.42%)

125(42.96%)

≥ 28

8(2.78%)

16(5.59%)

28(9.72%)

44(15.12%)

SBP (mmHg)

124.64 ± 17.79

123.86 ± 19.67

126.60 ± 17.73

130.06 ± 21.17

< 0.001

DBP (mmHg)

73.02 ± 10.47

73.71 ± 12.21

74.17 ± 10.45

76.01 ± 11.72

0.011

TC (mmol/L)

5.25 ± 0.89

5.23 ± 0.91

5.05 ± 0.94

5.02 ± 0.96

0.002

TG (mmol/L)

1.00(0.82–1.28)

1.17(0.86–1.50)

1.31(1.02–1.72)

1.72(1.25–2.25)

< 0.001

LDL-C (mmol/L)

2.83 ± 0.72

3.05 ± 0.78

3.03 ± 0.81

3.05 ± 0.79

< 0.001

TP (g/L)

71.62 ± 4.10

71.53 ± 3.57

71.73 ± 3.81

72.23 ± 3.94

0.186

Hb (g/L)

128.90 ± 11.80

131.33 ± 10.62

130.64 ± 11.31

132.96 ± 10.83

< 0.001

TB (µmol/L)

11.13 ± 4.44

10.72 ± 4.39

10.27 ± 3.58

10.68 ± 4.26

0.155

ALT (U/L)

14.00(11.07–18.42)

15.10(11.20–19.80)

15.65(12.30-21.32)

17.20(13.15–23.95)

< 0.001

AST (U/L)

18.70(15.60-22.42)

18.55(15.00-22.78)

18.50(15.90-22.92)

18.90(16.20-22.75)

0.408

ALP (U/L)

62.98 ± 21.51

64.60 ± 18.92

69.89 ± 20.10

73.23 ± 19.70

< 0.001

GGT (U/L)

14.50(11.80–17.80)

15.75(12.43–20.60)

17.40(13.67–23.82)

19.30(15.40–26.10)

< 0.001

FBG (mmol/L)

4.91 ± 0.49

4.93 ± 0.45

5.03 ± 0.52

5.14 ± 0.50

< 0.001

Serum creatinine (µmol/L)

55.58 ± 7.76

56.86 ± 8.18

56.48 ± 8.24

59.55 ± 11.98

< 0.001

LFC (%)

5.22 ± 2.63

6.02 ± 3.29

7.13 ± 3.34

9.39 ± 5.67

< 0.001