Table 1 Patient characteristics.

From: Biochemical failure-free survival of 18F-rhPSMA-7 and 18F-flotufolastat PET-guided salvage radiotherapy for patients with recurrent prostate cancer

 

All patients

N = 110

Patients with C-SRT

n = 28

Patients with 18F-rhPSMA-7/18F-flotufolastat-guided SRT

n = 82

p

Age, years

 Median

72.0

69.5

73.0

0.126

 Range

50–84

57–79

50–84

Treatment Fields, n (%)

 PB

25 (23%)

25 (89%)

 < 0.001*

 PB + ePLN

3 (2.7%)

3 (11%)

 PB/SIB

52 (47%)

52 (63%)

 PB/SIB + ePLN

9 (8.2%)

9 (11%)

 PB + ePLN/SIB

7 (6.4%)

7 (8.5%)

 PB/SIB + ePLN/SIB

9 (8.2%)

9 (11%)

 ePLN/SIB

5 (4.5%)

5 (6.1%)

Postoperative Tumor Classification, n (%)

 pT2a

9 (8.2%)

4 (14%)

5 (6.1%)

0.645

 pT2b

4 (3.6%)

1 (3.6%)

3 (3.7%)

 pT2c

43 (39%)

8 (29%)

35 (43%)

 pT3

1 (0.9%)

0 (0.0%)

1 (1.2%)

 pT3a

30 (27%)

9 (32%)

21 (26%)

 pT3b

21 (19%)

6 (21%)

15 (18%)

 Missing

2 (1.8%)

0 (0.0%)

2 (2.4%)

Postoperative Nodal Status, n (%)

 Negative (pN0)

95 (86%)

24 (86%)

71 (87%)

0.720

 Positive (pN1)

11 (10%)

3 (11%)

8 (9.8%)

 Unknown (pNx)

2 (1.8%)

1 (3.6%)

1 (1.2%)

 Missing

2 (1.8%)

0 (0.0%)

2 (2.4%)

Postoperative Surgical Margin, n (%)

 Negative (R0)

76 (69%)

17 (61%)

59 (72%)

0.446

 Positive (R1)

23 (21%)

7 (25%)

16 (20%)

 Unknown (Rx)

6 (5.5%)

3 (11%)

3 (3.7%)

 Missing

5 (4.5%)

1 (3.6%)

4 (4.9%)

ISUP Grade Group, n (%)

 1 (≤ 6)

10 (9.1%)

3 (11%)

7 (8.5%)

0.116

 2 (3 + 4 = 7)

37 (34%)

9 (32%)

28 (34%)

 3 (4 + 3 = 7)

36 (33%)

5 (18%)

31 (38%)

 4 (8)

9 (8.2%)

3 (11%)

6 (7.3%)

 5 (9–10)

14 (13%)

7 (25%)

7 (8.5%)

 Missing

4 (3.6%)

1 (3.6%)

3 (3.7%)

PSA before RT, ng/mL

 Median

0.39

0.32

0.45

0.029*

 Range

0.20–22.00

0.20–3.97

0.20–22.00

Additive ADT

 Yes

75 (68%)

23 (82%)

52 (63%)

0.066

 No

35 (32%)

5 (18%)

30 (37%)

  1. * = significant result. PSA, prostate-specific antigen; RT, radiotherapy; ng/mL, nanogram/milliliter; ADT, androgen deprivation therapy; ePLN, elective pelvic lymph nodes; ISUP, International Society of Urological Pathology; PB, prostate bed; SIB, simultaneous-integrated boost.