Table 3 Correlation between PD-L1 expression and clinicopathological factors in HBV-associated HCC.
Factors | N | PD-L1 | P | Spearman correlation coefficient | |
|---|---|---|---|---|---|
Low expression (n = 57) | High expression (n = 10) | ||||
TNM stage (%) | 0.003 | 0.260* | |||
I | 33 | 32(56.1) | 1 (10.0) | ||
II | 22 | 18 (31.6) | 4 (40.0) | ||
III | 11 | 7 (12.3) | 4 (40.0) | ||
IV | 1 | 0 (0.0) | 1 (10.0) | ||
Histopathological grading (%) | 0.025 | 0.214 | |||
Low | 13 | 8 (14.0) | 5 (50.0) | ||
Intermediate | 49 | 44 (77.2) | 5 (50.0) | ||
High | 5 | 5 (8.8) | 0 (0.0) | ||
Number of tumors (%) | 0.343 | ||||
1 | 57 | 50 (87.7) | 7 (70.0) | ||
2 | 7 | 5 (8.8) | 2 (20.0) | ||
>2 | 3 | 2 (3.5) | 1 (10.0) | ||
Maximum diameter of primary tumor (cm) (mean ± SD) | 67 | 6.95 ± 4.32 | 8.34 ± 6.49 | 0.389 | |
CK19 (mean ± SD) | 67 | 0.46 ± 1.74 | 0.60 ± 1.265 | 0.804 | |
CK18 (mean ± SD) | 67 | 5.23 ± 4.09 | 4.10 ± 4.38 | 0.429 | |
CD34 (mean ± SD) | 67 | 2.74 ± 3.60 | 3.70 ± 3.95 | 0.444 | |
Glypican-3 (mean ± SD) | 67 | 3.77 ± 3.83 | 5.00 ± 4.37 | 0.363 | |
Hepar-1 (mean ± SD) | 67 | 2.39 ± 3.53 | 0.50 ± 1.27 | 0.102 | |
Ki67(%) (mean ± SD) | 67 | 24.91 ± 20.41 | 41.50 ± 21.56 | 0.024 | 0.262* |
