Table 4 Metabolite Differences between subclinical hypothyroidism (SCH) and Control in WS.

From: Metabolic profiling reveals altered amino acid and fatty acid metabolism in children with Williams Syndrome

Metabolite

FC

log2(FC)

p value

FDR

AA

Asa

1.60

0.67676

0.035581a

0.31084

 

Cit

1.19

0.25594

0.026211a

0.31084

 

Gln

1.18

0.23825

0.00063254a

0.037953*

 

Asp

0.84

−0.24555

0.017633a

0.31084

 

Kyn

0.84

−0.25963

0.036264a

0.31084

 

Glu

0.67

−0.56961

0.0050999b

0.102

FA

C18:1 OA

1.67

0.74317

0.0021983b

0.065948

 

C14 MA

1.43

0.51882

0.027513b

0.23582

 

C16:1 PLA

1.30

0.38325

0.03503b

0.26272

a. T-test, b. Mann-Whitney U tests, *0.01＜P＜0.05

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