Table 1 Regression and validation parameters for spectrophotometric determination of SAF with SAF DEG.

From: Stability-indicating spectrophotometric quantification of safinamide in the presence of its possible degradation product

Parameters

FSD

DWL

SAF

SAF deg

SAF

SAF deg

Range

5–30

5–15

5–30

2–15

Correlation coefficient

0.9993

0.9996

0.9994

0.9995

Slope

0.092

0.044

0.008

0.011

Intercept

1.187

0.060

− 0.020

− 0.017

LODa

1.138

0.437

1.039

0.440

LOQb

3.450

1.324

3.149

1.335

Wavelength

235 nm

242.3

223.6–228 nm

220–233 nm

Accuracy (Recovery%c ± SD)

100.528 ± 0.655

100.140 ± 0.352

99.544 ± 0.112

99.981 ± 0.275

Precision

Intradayd

0.218

0.726

0.516

0.602

%RSD

Interdayd

0.689

0.887

1.034

0.713

  1. a3.3*SD of intercept/slope.
  2. b10*SD of intercept/slope.
  3. cAverage of nine estimations.
  4. dRSD% of nine estimations.
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