Fig. 1

Methods. (A) Experimental setup with the small-animal stereotactic frame and microscope. The middle image displays an animal fixed with three fixed points: two pins in the ear canals and one clamp on the nose. The last image (to the right) is a microsurgical view of the syringe in the skull of an animal through the burr hole. (B) Whole-brain extraction post-mortem, and preparation for histological and immunohistochemical analyses.