Table 4 The prevalence of co-sensitization between Tenebrio molitor and other invertebrate allergens, categorized into protein families.

From: IgE-based analysis of sensitization and cross-reactivity to yellow mealworm and edible insect allergens before their widespread dietary introduction

Phylum

Class

Order

Family

Species

Allergen name

Protein Family

% of positive test

Correlation coefficient*

        

p-value (two-tailed test)

Nematoda

Secernantea

Ascaridida

Anisakidae

Anisakis simplex

rAni s 1

Serine protease inhibitors

3.00%

0.17

        

0.693

     

rAni s 3

Tropomyosin

38.60%

0.88

        

< 0.001

Arthropoda

Malacostraca

Decapoda

Crangonidae

Crangon

rCra c 6

Troponin C

8.20%

− 0.06

        

0.805

   

Penaeidae

Penaeus monodon

nPen m 1

Tropomyosin

36.00%

0.91

        

< 0.001

     

rPen m 2

Arginine kinase

14.20%

0.36

        

0.026

     

rPen m 3

Myosin light chain 2

4.90%

0.2

        

0.523

     

rPen m 4

Sarcoplasmic calcium binding protein

5.60%

0.06

        

0.84

 

Insecta

Blattodea

Blattidae

Blatella germanica

rBla g 1

Nitrile specifier, microvilli-like protein with unknown function

0.40%

 
     

rBla g 2

Inactive aspartic protease

2.20%

− 0.03

        

0.957

     

rBla g 4

Lipocalin

8.60%

0.05

        

0.816

     

rBla g 5

Glutathione S-transferase

0.40%

 
     

rBla g 9

Arginine kinase

21.70%

0.33

        

0.013

    

Periplaneta americana

rPer a 7

Tropomyosin

39.00%

0.92

        

< 0.001

  

Coleoptera

Tenebrionidae

Tenebrio molitor

Ten m

  

1

        

.

  

Hymenoptera

Apidae

Apis mellifera

nApi m 1

Phospholipase A2

5.20%

0

        

0.994

     

rApi m 10

Icarapin var.2

5.20%

− 0.35

        

0.221

   

Vespidae

Vespula vulgaris

rVes v 1

Phospholipase A1

4.90%

0.16

        

0.609

     

rVes v 5

Antigen 5

19.10%

− 0.08

        

0.597

    

Polistes dominulus

rPol d 5

Antigen 5

7.10%

0.66

        

0.002

 

Arachnida

Ixodida

Argasidae

Argas reflexus

rArg r 1

Lipocalin

7.10%

0.17

        

0.499

  

Sarcoptiformes

Echimyopodidae

Blomia tropicalis

rBlo t 5

Group 5/21 allergen

38.60%

0.72

        

< 0.001

     

rBlo t 10

Tropomyosin

13.10%

0.5

        

0.002

     

rBlo t 21

Group 5/21 allergen

10.50%

0.35

        

0.07

   

Pyroglyphidae

Dermatophagoides farinae

rDer f 1

Cysteine protease

29.60%

0.24

        

0.032

     

rDer f 2

NPC2 family

40.10%

0.15

        

0.117

   

Pyroglyphidae

Dermatophagoides pteronyssinus

rDer p 1

Cysteine protease

33.30%

0.02

        

0.869

     

rDer p 2

NPC2 family

39.70%

0.17

        

0.088

     

rDer p 5

Group 5/21 allergen

21.00%

0.00

        

0.993

     

rDer p 7

Bacterial permeability increasing like protein

15.00%

− 0.17

        

0.307

     

rDer p 10

Tropomyosin

39.30%

0.84

        

< 0.001

     

rDer p 11

Paramyosin

4.90%

0.48

        

0.096

     

rDer p 20

Arginine kinase

19.10%

0.34

        

0.015

     

rDer p 21

Group 5/21 allergen

15.70%

0.18

        

0.263

     

rDer p 23

Peritrophin-like protein domain

37.10%

0.08

        

0.416

   

Glycyphagidae

Glycyphagus domesticus

rGly d 2

NPC2 family

28.10%

0.04

        

0.756

    

Lepidoglyphus destructor

rLep d 2

NPC2 family

32.60%

0.09

        

0.421

   

Acaridae

Tyrophagus putrescentiae

rTyr p 2

NPC2 family

9.70%

0.5

        

0.009

  1. * Spearman rank correlation coefficient.