Fig. 4
From: Role of P2 X7 receptor during focused ultrasound induced blood brain barrier modulation
No evidence of death signals after LiFUS stimulation. (a) Results of ATP quantification in the lesion. The bar graph shows the normalized level of ATP relative to that of control. # p < 0.05, ## p < 0.01, ### p < 0.001; compared to Con, * p < 0.05; compared to 1 h. (b) Western blot results for NF-κB. The bar graph shows the normalized level of the receptor relative to that of the control. Band intensity images for each group are included. *** p < 0.001; compared to 1 h. (c,d) RT-PCR results for caspase 3/9. No significant differences were observed among the groups. All data are represented as mean ± SD (n = 5). One-way ANOVA with Tukey’s multiple comparison test was performed. (e) Representative images of the TUNEL assay (white arrow) and H&E images of each group. Scale bar: 20 μm for TUNEL and 100 μm for H&E images.
