Fig. 1
From: A multicenter study on TROP2 as a potential targeted therapy for extramammary Paget disease in Japan
TROP2 expression in patients’ paired EMPD samples. Representative images of TROP2 staining (in red) in paired samples of primary and metastatic EMPD. TROP2 is highly expressed in the tumor as well as in normal epidermal keratinocytes. EMPD tumor cells are highlighted by CK7 staining (in brown), but epidermal keratinocytes are not (negative staining for CK7). Most primary and metastatic lesions show strong and diffuse expression of TROP2 with high H-scores (p = 0.185, Wilcoxon matched-pairs signed rank test). Bars = 200 µm.
